SELDOM Pharma

Telmisartan is a nonpeptide angiotensin II receptor antagonist which selectively and insurmountably inhibits the angiotensin II AT1 receptor subtype without affecting other receptor systems involved in cardiovascular regulation and used in the management of hypertension.

TELSEL 40 is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents. TELSEL 40 is indicated for reduction of the risk of myocardial infarction, stroke.

Dosage must be individualized. The usual starting dose is TELSEL40 is once a day.

Each box contains 10 strips of 10 tablets each.

Telmisartan is a nonpeptide angiotensin II receptor antagonist which selectively and insurmountably inhibits the angiotensin II AT1 receptor subtype without affecting other receptor systems involved in cardiovascular regulation and used in the management of hypertension.
Hydrochlorothiazide is a thiazide diuretic. Thiazides affect the renal tubular mechanisms of electrolyte reabsorption, directly increasing excretion of sodium salt and chloride in approximately equivalent amounts. Indirectly, the diuretic action of hydrochlorothiazide reduces plasma volume, with consequent increases in plasma renin activity, increases in aldosterone secretion, increases in urinary potassium loss,and decreases in serum potassium. The renin- aldosterone link is mediated by angiotensin II, so coadministration of an angiotensin II receptor antagonist tends to reverse the potassium loss associated with these diuretics.

TELSEL-H (telmisartan and hydrochlorothiazide) tablets are indicated for the treatment of hypertension. This fixed dose combination is not indicated for initial therapy.

The usual starting dose of telmisartan is 40 mg once a day; blood pressure response is dose related over the range of 20-80 mg. Hydrochlorothiazide is effective in doses of 12.5 mg to 50 mg once daily.

Each box contains 10 strips of 10 tablets each.